Stop Stigma Image.jpeg



Please read the important information below in red text regarding second doses of Jynneos vaccines. 

What is Monkeypox? 
Monkeypox is a rare illness caused by a virus that is related to the smallpox virus. While generally less severe and much less infectious than smallpox, monkeypox can be a serious illness. It causes fever, headache, muscle aches, backache, swollen lymph nodes, a general feeling of discomfort, exhaustion, and severe rash. The illness lasts 2-4 weeks. 


How does it spread? 
The virus is not easily spread between people, but it can spread through contact with bodily fluids as well as through large respiratory droplets that do not travel more than a few feet.


Why is it recommended? 
Vaccines can be used to help prevent symptoms when given before exposure for those that qualify and/or who may be at higher risk. 

Who should get vaccinated? 

Men who have sex with men (MSM) and/or transgender individuals who meet at least one of the following criteria: 

      •    have tested positive for an STI in the past two months

      •    had 2+ sexual partners in the last 3 weeks

      •    attended or worked at a commercial sex venue in the last 3 weeks

      •    had anonymous sex in past 3 weeks

      •    engaged in transactional sex (sex work) in the past 3 weeks

Anyone, regardless of gender identity or sexual orientation who:
      •    engaged in transactional sex or sex work in past 3 weeks
      •    was identified by SCPH as a close contact of someone who has tested positive for monkeypox

If you have additional questions regarding eligibility, please contact your county department of public health. Sacramento's Department of Public Health may be reached by emailing or calling 916-875-5881.

What vaccine is used? 

JYNNEOS is a vaccine indicated for prevention of monkeypox disease. It is administered as two subcutaneous injections four weeks apart. People who receive JYNNEOS are not considered vaccinated until 2 weeks after they receive the second dose of the vaccine.

Important information regarding second doses of JYNNEOS vaccine:

In accordance with guidance from the California Department of Public Health, Sacramento County Public Health and our vaccine partners including Pucci's Pharmacy will prioritize Jynneos first doses to as many eligible individuals as possible and will defer second doses until sufficient supply is received. Given the rapid increase of cases and very limited number of vaccines, this strategy will allow more people to receive a dose. 

Sacramento County Public Health and vaccine partners including Pucci's Pharmacy will notify the community when vaccine supply is available for second doses to complete the vaccine series. Even if a person receives one dose, a second dose can be administered without having to restart the series, even if the second dose is given after the minimum interval of four weeks.

In limited circumstances, individuals with confirmed immunosuppression can receive a second dose by having their provider complete an attestation​ regarding their eligibility and bringing to a public monkeypox vaccine clinic.​ Click here to download the attestation form for your medical provider to complete. As an alternative, you may show the pharmacist at Pucci's your most recent labs via MyChart login or similar to your medical record thereby confirming your CD4+ count is < 200 and we will be able to administer your second dose 28 days after the first dose. 


According to the US Food & Drug Administration, Jynneos is indicated for prevention of smallpox and monkeypox disease in adults. However, since no vaccine is 100 percent effective, and most individuals will only be vaccinated with one dose until supplies are sufficient, it is important for individuals to reduce their risk of potential exposures to monkeypox both before and after being vaccinated. 

Is the vaccine effective? 
Smallpox and monkeypox vaccines are effective at protecting people against monkeypox when given before exposure to monkeypox. Experts also believe that vaccination after a monkeypox exposure may help prevent the disease or make it less severe.

Will I have side effects? 
Most people who get the monkeypox vaccine have only minor reactions, like mild fever, tiredness, swollen glands, and redness and itching at the place where the vaccine is given.